According to the newest issue of Game Informer, Max Payne 3 will be set 12 years after Max Payne 2 in Sao Paulo, Brazil. The storyline follows Max Payne once more after he left New York city to get away from everything, and now works as security for a wealthy family in Brazil. It’s also said that he is addicted to painkillers (seems appropriate) which will have some kind of impact on the gameplay. It will feature a new cover system and will be using Rockstar’s RAGE engine (same used in Grand Theft Auto 4), and will also feature more destructable environments and online multiplayer.
I was a big fan of the original two games in the series so I am looking forward to part 3.